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효소 활성에 영향을 미치는 요인 Factors affecting enzyme activity

MagicCafe 2022. 11. 14. 07:24
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Enzyme activity can be affected by a variety of factors, such as temperature, pH, and concentration.
Enzymes work best within specific temperature and pH ranges, and sub-optimal conditions can cause an enzyme to lose its ability to bind to a substrate.
  • Temperature: Raising temperature generally speeds up a reaction, and lowering temperature slows down a reaction. However, extreme high temperatures can cause an enzyme to lose its shape (denature) and stop working.
  • pH: Each enzyme has an optimum pH range. Changing the pH outside of this range will slow enzyme activity. Extreme pH values can cause enzymes to denature.
  • Enzyme concentration: Increasing enzyme concentration will speed up the reaction, as long as there is substrate available to bind to. Once all of the substrate is bound, the reaction will no longer speed up, since there will be nothing for additional enzymes to bind to.
  • Substrate concentration: Increasing substrate concentration also increases the rate of reaction to a certain point. Once all of the enzymes have bound, any substrate increase will have no effect on the rate of reaction, as the available enzymes will be saturated and working at their maximum rate.


효소 활성은 온도, pH, 농도와 같은 다양한 요인에 의해 영향을 받을 수 있다

효소는 특정 온도와 pH 범위 내에서 가장 잘 작동하며, 차선의 조건은 효소가 기질에 결합하는 능력을 잃게 할 수 있다.

온도: 온도를 높이면 일반적으로 반응이 빨라지고, 온도를 낮추면 반응이 느려진다. 그러나, 극도로 높은 온도는 효소가 그것의 모양(변성)을 잃고 작동을 멈추게 할 수 있다.


pH: 각각의 효소는 최적의 pH 범위를 가지고 있습니다. pH가 이 범위를 벗어나면 효소 활성이 느려진다. 극단적인 pH 값은 효소의 변성을 유발할 수 있다.


효소 농도: 결합할 수 있는 기질이 있는 한, 효소 농도를 증가시키면 반응이 빨라질 것이다. 일단 모든 기질이 결합되면, 추가적인 효소가 결합할 것이 없기 때문에 반응은 더 이상 빨라지지 않을 것이다.


기질 농도: 기질 농도를 증가시키면 반응 속도도 일정 지점까지 증가한다. 일단 모든 효소가 결합하면, 사용 가능한 효소가 포화되고 최대 속도로 작동하기 때문에, 기질 증가는 반응 속도에 영향을 미치지 않을 것이다.

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